Prof. Denis Duboule

Duboule

+41 22 379 67 71
4004 (Sciences III)
4, Bvd d'Yvoy
CH-1205 Geneva
Switzerland

Publications

Science. 2014 Nov 21;346(6212):1004-6. doi: 10.1126/science.1257493. Pubmed

Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci.

Lonfat N, Montavon T, Darbellay F, Gitto S, Duboule D

School of Life Sciences, Ecole Polytechnique Federale de Lausanne, 1015 Lausanne, Switzerland. School of Life Sciences, Ecole Polytechnique Federale de Lausanne, 1015 Lausanne, Switzerland. School ...

Methods Mol Biol. 2014;1196:89-102. doi: 10.1007/978-1-4939-1242-1_6. Pubmed

The Genetics of Murine Hox Loci: TAMERE, STRING, and PANTHERE to Engineer Chromosome Variants.

Tschopp P, Duboule D

Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, USA.

Nature. 2014 Jul 3;511(7507):46-51. doi: 10.1038/nature13289. Epub 2014 Jun 18. Pubmed

Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs.

Lopez-Rios J, Duchesne A, Speziale D, Andrey G, Peterson K A, Germann P, Unal E, Liu J, Floriot S, Barbey S, Gallard Y, Muller-Gerbl M, Courtney A D, Klopp C, Rodriguez S, Ivanek R, Beisel C, Wicki...

1] Developmental Genetics, Department Biomedicine, University of Basel, CH-4058 Basel, Switzerland [2]. 1] Developmental Genetics, Department Biomedicine, University of Basel, CH-4058 Basel, Switze...

Elife. 2014 Apr 29;3:e02557. doi: 10.7554/eLife.02557. Pubmed

Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci.

Noordermeer D, Leleu M, Schorderet P, Joye E, Chabaud F, Duboule D

School of Life Sciences, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland. School of Life Sciences, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland. School of Life Sc...

Dev Cell. 2014 Apr 28;29(2):171-187. doi: 10.1016/j.devcel.2014.03.008. Epub 2014 Apr 17. Pubmed

Evolving Hox Activity Profiles Govern Diversity in Locomotor Systems.

Jung H, Mazzoni E O, Soshnikova N, Hanley O, Venkatesh B, Duboule D, Dasen J S

Howard Hughes Medical Institute, NYU Neuroscience Institute, Department of Neuroscience and Physiology, New York University School of Medicine, New York, NY 10016, USA. Department of Biology, New Y...

Cell. 2014 Feb 13;156(4):856-856.e1. doi: 10.1016/j.cell.2014.01.060. Pubmed

SnapShot: Hox Gene Regulation.

Andrey G, Duboule D

School of Life Sciences, Ecole Polytechnique Federale, Lausanne 1015, Switzerland. School of Life Sciences, Ecole Polytechnique Federale, Lausanne 1015, Switzerland; Department of Genetics and Evol...

Elife. 2014 Aug 14;3:e03058. doi: 10.7554/eLife.03058. Pubmed

Considerations when investigating lncRNA function in vivo.

Bassett A R, Akhtar A, Barlow D P, Bird A P, Brockdorff N, Duboule D, Ephrussi A, Ferguson-Smith A C, Gingeras T R, Haerty W, Higgs D R, Miska E A, Ponting C P

Andrew R Bassett is in the MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom. andrew.bassett@path.ox.ac.uk. Asifa Akhtar is ...

PLoS Biol. 2014 Jan;12(1):e1001773. doi: 10.1371/journal.pbio.1001773. Epub 2014 Jan 21. Pubmed, link, 2.28 MB

Conservation and divergence of regulatory strategies at hox Loci and the origin of tetrapod digits.

Woltering J M, Noordermeer D, Leleu M, Duboule D

Department of Genetics and Evolution, University of Geneva, Geneva, Switzerland. School of Life Sciences, Federal Institute of Technology, Lausanne, Switzerland. School of Life Sciences, Federal In...

PLoS Genet. 2013 Nov;9(11):e1003951. doi: 10.1371/journal.pgen.1003951. Epub 2013 Nov 7. Pubmed

A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus.

Schorderet P, Lonfat N, Darbellay F, Tschopp P, Gitto S, Soshnikova N, Duboule D

National Research Center 'Frontiers in Genetics', Geneva, Switzerland ; School of Life Sciences, Federal Institute of Technology (EPFL), Lausanne, Switzerland.

Nature. 2013 Oct 24;502(7472):499-506. doi: 10.1038/nature12753. Pubmed

Topology of mammalian developmental enhancers and their regulatory landscapes.

de Laat W, Duboule D

Hubrecht Institute-KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, the Netherlands.