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How mammary glands appeared in the course of evolution

  • news
  • 15-11-2016

Elements of the regulatory networks controlling Hox gene expression were hijacked, enabling some of these genes to be reused to form mammary buds. This study, published during the week of November 14, 2016 in PNAS, was led by Leonardo Beccari, from the team of Denis Duboule.

Africa's Noon

  • news
  • 26-10-2016

On November 7, at 12:15 room M2170, Anne Mayor and Michel Milinkovitch will present their work. Conference proposed by the International Affairs.

Colloque Wright 2016

  • news
  • 12-10-2016

This year, we will hear from specialists, including a Nobel Prize, in areas that are profoundly transformed by the advent of genomics.

Physics of Biology II international meeting

  • news
  • 19-09-2016

For the past fifteen years, an interest for Quantitative & Systems Biology has been raising in the scientific community. Major advances in this direction have been driven by the integration of physics and computer science approaches with innovative technological developments in molecular biology, optics, micro- and nano-manipulations. Although Quantitative & Systems Biology is very recent, it has already significantly spread through many fields of life sciences: genetics, biochemistry, cell biology, development, ecology and many others.

Professor Emi Nagoshi wins the 3R Award

  • news
  • 15-09-2016

The winner of this first edition of the 3R Award is Professor Emi Nagoshi, from the Department of Genetics and Evolution of the Faculty of Sciences, for her project entitled “A conserved role for p48 homologs in protecting dopaminergic neu­rons from oxidative stress”. She will receive her Award on Monday, September 19th at 9:45am.

H2020 should focus on innovative collaborative discovery research, not on technology readiness

  • news
  • 07-09-2016

To forge better links not only between university research laboratories but also with companies, there should be more room for bottom-up, collaborative research in the EU’s framework research programme – specifically in Horizon 2020’s pillars II and III. Today, the League of European Research Universities (LERU) issues a Note to call attention to this issue. Feel free to read the attached PDF.

2016 Louis-Jeantet Symposium

  • news
  • 01-09-2016

The fifth edition of the Louis-Jeantet Symposium will be organised by Denis Duboule, chairman of the Department of genetics and evolution at the Faculty of Science, University of Geneva, and professor at the EPFL School of life sciences, and by Konrad Basler, chairman of the Institute of Molecular Life Sciences, University of Zurich.

Hydra can modify its genetic program

  • news
  • 16-12-2015

Champion of regeneration, the freshwater polyp Hydra is capable of reforming a complete individual from any fragment of its body. It is even able to remain alive when all its neurons have disappeared. Researcher the University of Geneva have discovered how: cells of the epithelial type modify their genetic program by overexpressing a series of genes, among which some are involved in diverse nervous functions. Studying Hydra cellular plasticity may thus in uence research in the context of neurodegenerative diseases. The results are published in Philosophical Transactions, the journal of the Royal Society.

Discovery of the mutation responsible of amelanism in the corn snake

  • news
  • 24-11-2015

Researchers in the laboratory of Michel Milinkovitch have identified in the corn snake the mutation responsible for amelanism, a form of albinism due to a defect in the production of melanin (the black and brown pigments of the skin). The skin of the wild type corn snake exhibits a light orange background colour covered with a pattern of dark orange dorsal saddles and lateral blotches that are outlined with black. However, some individuals do not correspond to that standard morphology: they lack all signs of melanin in the skin and eyes. The Swiss team decided to search for the DNA mutation that determines that specific coloration. To this end, they bred wild-type corn snakes with amelanistic individuals and they sequenced each offspring born from that cross. “Thanks to that large amount of sequencing data, we identified the malfunctioning gene”, explains Milinkovitch. That gene is called OCA2 and codes for a receptor located in the membranes of intracellular compartments, called melanosomes, that contain melanin. This receptor controls the proper level of acidity allowing for the synthesis of melanin.

Reptilian Genomics and Transcriptomics make a leap forward

  • news
  • 14-11-2015

Reptiles are poorly represented in genomic and transcriptomic databases, hindering functional evolutionary and developmental studies in these lineages substantially more diverse than mammals. In addition, different authors have used different assembly and annotation protocols, inhibiting meaningful comparisons. To help filling this gap, two new studies, directed by Dr. Athanasia Tzika, generated two new resources: (i) the ‘Reptilian Transcriptomes Database 2.0’, which provides extensive annotation of transcriptomes and genomes from species covering the major reptilian lineages, and (ii) the draft genome of the corn snake, a species we promote as an excellent model for evolutionary developmental (EvoDevo) studies in squamate reptiles.

R2OBBIE-3D: scanning Life with high resolution

  • news
  • 08-06-2015

In a paper recently published in PLOS ONE, the laboratory of Prof. Michel Milinkovitch reports on R2OBBIE-3D, a robotic integrated system that generates accurate 3D models of biological objects

Four to eleven species of Panther Chameleons uncovered

  • news
  • 26-05-2015

Recently, results of biophysical analyses performed by the group of Prof Michel Milinkovitch made the buzz as the researchers discovered that chameleons shift colour through active tuning of a lattice of guanine nanocrystals within specialised skin cells rather that by dispersion/aggregation of pigments.

The fly’s time

  • news
  • 21-05-2015

The biological clockwork of human beings and flies is comparable

  • event
  • Life Science Seminar Series
  • 23.05.2017 16:15, A100 (Sciences II)

Petra Schwille (Max-Planck-Institute of Biochemistry, Dept. Cellular and Molecular Biophysics, Martinsried, Germany).
hosted by: PhD Association .

  • event
  • Life Science Seminar Series
  • 02.05.2017 16:15, A100 (Sciences II)

Mike Sheetz (Mecanobiology Institute, Singapore).
hosted by: Sandra Citi .

  • event
  • Geneva Plant Seminars
  • 26.04.2017 12:15, 1S059 (Sciences III)

Dr. Mauro Tonolla (SUPSI).
hosted by: Michel Goldschmidt-Clermont .

  • event
  • Life Science Seminar Series
  • 14.02.2017 16:15, A100 (Sciences II)

Alejandro Sanchez Alvarado (Stowers Institute for Medical Research, Kansas City, USA).
hosted by: Brigitte Galliot .

  • event
  • Life Science Seminar Series
  • 13.12.2016 16:15, A100 (Sciences II)

William Martin (Institute Molecular Evolution, Düsseldorf, Germany).
hosted by: Jean-Claude Martinou .