offres d'emploi
Genetic and developmental study of the reptilian skin coloration
Closing Date: 15 November 2021
The LANE laboratory at the University of Geneva (Switzerland) is seeking a creative and highly motivated PhD student to work on mapping mutations affecting skin colour traits in the corn snake. The working language of the laboratory is English.
In the context of highly multidisciplinary studies investigating the development of skin colour patterns in the corn snake, we are looking for a student with strong interest in molecular developmental biology to assist in mapping corn snake colour and colour pattern traits. Advanced computer skills are a plus. The successful candidate will interact with a multidisciplinary team of physicists, computer scientists and biologists and will be trained in state-of-the-art imaging techniques and molecular developmental approaches.
References
Ullate-Agote A. and Tzika A.C.
Characterization of the Leucistic Texas Rat Snake Pantherophis obsoletus
Frontiers in Ecology and Evolution (2021)
Ullate-Agote A., Burgelin I., Debry A., Langrez C., Montange F., Peraldi R., Daraspe J., Kaessmann H., Milinkovitch, M. C. and Tzika A. C.
Genome mapping of a LYST mutation in corn snakes indicates that vertebrate chromatophore vesicles are lysosome-related organelles
Proceedings of the National Academy of Sciences (PNAS) (2020)
Qualifications & skills
- Master in biology-related sciences.
- Candidates should have a strong inner drive, independence, and willingness to work in a highly interdisciplinary team.
- A good level of spoken and written English is essential.
Laboratory
The team’s projects are interdisciplinary, and aim at understanding the genetic determinism of skin colour patterns (especially in snakes and lizards) but also skin appendages (scales, hair, and spines) in amniotes. Besides standard molecular biology methods, we use confocal and light-sheet microscopy imaging, electron microscopy, mass spectrometry and deep sequencing.
Environment
The University of Geneva (UNIGE) is highly-renowned for its research and is among the best universities in the world. Geneva is an international city occupying a privileged geographical situation.
Contact
Interested applicants are invited to send a motivation letter with a short statement of research interests and a CV combined in a single PDF document to:
Dr. Athanasia Tzika (athanasia.tzika@unige.ch)
The selection of the successful candidate will be made through the ‘Open Call’ of the Life Sciences PhD School (https://lifesciencesphd.unige.ch - deadline November 15, 2021).
PhD student position: Neurodegenerative disease research using Drosophila and mice
We are seeking a highly motivated PhD student to join our effort to understand the mechanisms underlying neurodegenerative disorders. We address this question from multiple angles, including the role neuroprotective transcription factors, links between dopaminergic neurodegeneration and circadian/ sleep disturbances, and the role of neuroinflammation.
The student will conduct a challenging project that takes advantage of both fly and mouse models. Candidate should have a Master’s degree in molecular biology, genetics, neurobiology, cell biology or related areas and hands-on experiences in molecular biology. Demonstrated academic achievement and proficiency in English are desirable. The project requires tight collaborations within and outside our group, thus the successful candidate should be an excellent team-player.
Who we are
The laboratory of Emi Nagoshi in the Department of Genetics and Evolution at the University of Geneva. http://genev.unige.ch/en/users/Emi-Nagoshi/unit
What we offer
The student will work in a small but highly interactive group, and will be closely supervised by the group leader. English is the language used in the lab. He/she will join the International PhD program in Molecular Biosciences at the University of Geneva or Lemanic Neuroscience Doctoral School. The salary and benefits are based on the Swiss National Science Foundation standard.
Start: Immediately or as agreed upon
To apply
Please send a CV, a brief statement of research interest in English, and the names and contact information of 2 references via e-mail to: Emi.Nagoshi@unige.ch
Master position – Mapping mutations affecting skin colour traits in the corn snake
n the context of highly multidisciplinary studies investigating the development of skin colour patterns in the corn snake, we are seeking creative and highly motivated students with strong interest in molecular developmental biology to assist in mapping corn snake colour and colour pattern traits. The successful candidates will interact with a multidisciplinary team of physicists, computer scientists and biologists and will be trained in state-of-the-art imaging techniques and molecular developmental approaches.
Contact Dr. Athanasia C. Tzika (athanasia [dot] tzika [at] unige.ch) for details.
Master position – Modelling variation & complexity of animal forms
In the context of highly multidisciplinary studies investigating the development of skin appendages (project 1) and skin colour patterns (project 2) in vertebrates, we are seeking creative and highly motivated students with strong interests and skills in mathematical modelling and numerical simulations of physical processes (reaction-diffusion, mechanics, …). The successful candidates will interact with a multidisciplinary team of physicists, computer scientists and biologists (the latter using state-of-the-art imaging techniques and molecular developmental approaches).
Contact Prof. Michel C. Milinkovitch (michel [dot] milinkovitch [at] unige.ch) for details.
Master position – Mapping mutations affecting skin colour traits in the leopard geckos
In the context of highly multidisciplinary studies investigating the development of skin colour patterns in the leopard geckos, we are seeking creative and highly motivated students with strong interest in molecular developmental biology to assist in mapping leopard gecko colour and colour pattern traits. The successful candidates will interact with a multidisciplinary team of physicists, computer scientists and biologists and will be trained in state-of-the-art imaging techniques and molecular developmental approaches.
Contact Dr. Athanasia C. Tzika (athanasia [dot] tzika [at] unige.ch) for details.
Physics of biological morphogenesis: Position for a theoretical physicist in Switzerland
We offer several positions for outstanding, highly motivated, and creative theoretical physicists or applied mathematicians, at the postdoc or PhD student level, in the Salbreux group. Projects are at the interface of physics and biology and involve analytical theory, numerical simulations, and data analysis, in close collaboration with experimental groups. The successful candidates will investigate morphogenetic processes and self-organization at the level of cells and tissues in biological systems.
Candidates must have a master degree in physics (for a PhD student position) or a PhD in theoretical physics or a related field (for a postdoctoral position). An expertise in biology is welcome but is not mandatory. The positions are for 3 to 5 years.
The University of Geneva (UNIGE) is world-renowned for its research and is among the top 1% best universities in the world. We offer an attractive research environment and salaries according to swiss standards.
References: Patterning and growth control in vivo by an engineered GFP gradient, Science, 2020; Mechanochemical Crosstalk Produces Cell-Intrinsic Patterning of the Cortex to Orient the Mitotic Spindle, Current Biology, 2020; Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis, Nature, 2019; Stability and Roughness of Interfaces in Mechanically Regulated Tissues, Phys Rev Let, 2018, Mechanics of active surfaces, Phys Rev E, 2017; Active dynamics of tissue shear flow, New J. Phys, 2017, The Physical Basis of Coordinated Tissue Spreading in Zebrafish Gastrulation, Dev Cell, 2017.
How to Apply
Candidates must send their application — in the form of a single PDF file including a brief letter of interest, a CV, as well as contact information of two to three persons of reference — to Prof. Guillaume Salbreux.