A hidden Markov model for progressive multiple alignment.

  • publication
  • 13-08-2003

Löytynoja A, Milinkovitch MC. Bioinformatics 2003 Aug;19(12):1505-13.

Progressive algorithms are widely used heuristics for the production of alignments among multiple nucleic-acid or protein sequences. Probabilistic approaches providing measures of global and/or local reliability of individual solutions would constitute valuable developments.

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