Hox13-Mediated Dbx2 Regulation In Limbs Suggests Inter-Tad Sharing Of Enhancers.

  • publication
  • 27-01-2021

Beccari L, Jaquier G, Lopez-Delisle L, Rodriguez-Carballo E, Mascrez B, Gitto S, Woltering J, Duboule D. Dev Dyn 2021 Jan;():. 10.1002/dvdy.303.

During tetrapod limb development, the HOXA13 and HOXD13 transcription factors are critical for the emergence and organization of the autopod, the most distal aspect where digits will develop. Since previous work had suggested that the Dbx2 gene is a target of these factors, we set up to analyze in detail this potential regulatory interaction.

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