Time-sequenced transcriptomes of developing distal mouse limb buds: A comparative tissue layer analysis.

• publication
• 14-07-2021

Fernandez-Guerrero M, Zdral S, Castilla-Ibeas A, Lopez-Delisle L, Duboule D, Ros M. Dev Dyn 2021 Jul;():. 10.1002/dvdy.394.

The development of the amniote limb has been an important model system to study patterning mechanisms and morphogenesis. For proper growth and patterning, it requires the interaction between the distal sub-apical mesenchyme and the apical ectodermal ridge (AER) that involve the separate implementation of coordinated and tissue-specific genetic programs.

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