Demographic history was a formative mechanism of the genetic structure for the taste receptor TAS2R16 in human populations inhabiting Africa's Sahel/Savannah Belt.

  • publication
  • 01-12-2021

Kulichová I, Mouterde M, Mokhtar MG, Diallo I, Tříska P, Diallo YM, Hofmanová Z, Poloni ES, Černý V. Am J Phys Anthropol 2021 Nov;():. 10.1002/ajpa.24448.

Mode of subsistence is an important factor influencing dietary habits and the genetic structure of various populations through differential intensity of gene flow and selection pressures. Previous studies suggest that in Africa Taste 2 Receptor Member 16 (TAS2R16), which encodes the 7-transmembrane receptor protein for bitterness, might also be under positive selection pressure.

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