Regeneration: Signaling superhighways.

  • publication
  • 27-09-2023

Sun F, De Simone A, Poss KD. Curr Biol 2023 Sep;33(18):R947-R950. 10.1016/j.cub.2023.08.024. S0960-9822(23)01067-9.

Regeneration requires the collective effort of multiple organ systems. A recent study of planarian whole-body regeneration finds that Erk kinase activity propagates rapidly across the entire animal through longitudinal muscle cells to coordinate animal-wide wound responses and that this signal propagation is required for regeneration.

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