Regulatory and disruptive variants in the CLCN2 gene are associated with modified skin color pattern phenotypes in the corn snake.

• publication
• 27-03-2025

Montandon SA, Beaudier P, Ullate-Agote A, Helleboid PY, Kummrow M, Roig-Puiggros S, Jabaudon D, Andersson L, Milinkovitch MC, Tzika AC. Genome Biol 2025 Mar;26(1):73. 10.1186/s13059-025-03539-0. 10.1186/s13059-025-03539-0.

Snakes exhibit a broad variety of adaptive colors and color patterns, generated by the spatial arrangement of chromatophores, but little is known of the mechanisms responsible for these spectacular traits. Here, we investigate a mono-locus trait with two recessive alleles, motley and stripe, that both cause pattern aberrations in the corn snake.

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